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Is the fat loss itself unhealthy? I mean, can the lack of fat around legs/muscles be a bad enough thing that he should switch meds? I can't even pinch the skin around his legs. There appears to be honestly, no fat what-so-ever. That worries me. Response from download Dr. Henry download Fat loss from arms/legs has been linked to HIV infection with treatment. Fat increases around neck also can be associated with HIV treatment though that can occur in the general population. Some HIV meds are more linked to fat loss then others (particularly D4T and download AZT) so a discussion with his HIV provider about what switch options are reasonable is a good place to start. Treatment interventions that clearly put fat back on are not currently available though that is an area of intense research interest (in the US the ACTG may soon be studying the use of uridine supplement for that purpose).
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